Contribution of the Kinematic Theory in the Early Differential Diagnosis of the Parkinson's Disease
Recruiting · NCT06161636 · Observational (researchers observe without assigning treatment) · Lead sponsor: Centre hospitalier de l'Université de Montréal (CHUM)
View the official record on ClinicalTrials.gov →What this trial is about
The working hypotheses are as follows: #1 The processing of performance signals by automated lognormal segmentation and the extraction of the parameters of interest will make it possible to distinguish groups of patients from healthy elderly subjects. #2 The three instrumental approaches will not have the same degree of reliability as a predictive biomarker of clinical diagnosis established by consensus.
Who can take part
Age range
50 Years to 75 Years
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Being diagnosed with Parkinsonism including idiopathic Parkinson's disease or a related syndrome;
- Have motor symptoms of Parkinsonism for 6 years or less;
- Be a healthy volunteer subject in good general health with no prior neurological history;
- Age between 50-75 years old;
- If applicable, be able to safely leave home in the morning without having taken antiparkinsonian medication for the past 12 hours.
Exclusion criteria
- Major neurocognitive disorders;
- History of other neurological conditions, such as ischemic or hemorrhagic stroke, paralysis of a limb, traumatic brain injury, epilepsy, orofacial dystonia, essential tremor;
- History of oromandibular or laryngeal procedures;
- Uncorrected deafness;
- Any contraindication to pupillary dilation.
Where it is running
1 location listed.
- CHUM/Université de Montréal - Montreal, Quebec, Canada