The Effect of Treatment of Emphysema With Endobronchial Valves on the Diaphragm Mobility
Recruiting · NCT06163131 · Observational (researchers observe without assigning treatment) · Lead sponsor: Aarhus University Hospital
View the official record on ClinicalTrials.gov →What this trial is about
In some patients with chronic obstructive pulmonary disease (COPD) the breathlessness is caused by hyperinflation of the lungs. This causes difficulty breathing air out and makes it harder to breath in new air and limits the movement of the diaphram. The diaphragm is the muscle used for breathing between the chest and the stomach. Some of these patients can receive treatment with endobronchial valves, where one-ways are inserted into the bronchial system the let out some of the excess air, and thereby relieve breathlessness. The goal of this observational study is to investigate the effect of endobronchial valves on the mobility of the diaphragm in patients with chronic obstructive pulmonary disease. The main questions it aims to answer are: * If the movement of the diaphragm improves after treatment with endobronchial valves. * If there is a link between improvement of diaphragm function and improvement of symptoms, lung function and physical ability. * If ultrasound scan immediately after the treatment will predict which patients will benefit from the treatment. Participants will undergo ultrasound before, 1 day after and 90 days after the procedure, and lung function examinations from their already planned control visits will be collected.
Who can take part
Inclusion criteria
- Patients selected to receive treatment with endobronchial valves
- Signed informed consent
Exclusion criteria
- Neuromuscular disease interfering with diaphragm function
- Pleural effusion at time of preoperative or 90-days postoperative ultrasound
Where it is running
1 location listed.
- Aarhus University Hospital - Aarhus, Denmark