Enucleation of Pancreatic Tumor by Blocking Abdominal Trunk and Superior Mesenteric Artery
Recruiting · NCT06164769 · Interventional (participants receive a specific treatment) · Lead sponsor: Zhejiang University
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
Pancreatic enucleation could preserve more healthy pancreatic tissues and functions with a low recurrence risk. However, conventional enucleation can cause significant intraoperative bleeding, especially in which tumors in the pancreatic head, neck, and uncinate process of pancreas, as these tissues are rich in blood supply, mainly including the abdominal trunk and the superior mesenteric artery. In this study, we developed a novel method to control the pancreatic blood flow in laparoscopic enucleation--blocking the abdominal trunk and superior mesenteric artery with vascular occlusion clips in the process of resection, and evaluated its effectiveness and safety.
Who can take part
Inclusion criteria
- Benign or borderline tumors diagnosed pathologically, such as pancreatic neuroendocrine tumors, solid pseudopapillary tumors, and cystadenomas, without vascular invasion or distant metastasis
- Tumors sited in the pancreatic head, neck, and uncinate process of pancreas
- Blockade of both the abdominal trunk and superior mesenteric artery in the laparoscopic enucleation
Exclusion criteria
- Highly malignant pancreatic tumors, or tumors with infiltration or metastasis
- Tumors of the body and tail of the pancreas
- Transfer to LPD or laparotomy
Where it is running
1 location listed.
- the Second Affiliated Hospital of Zhejiang University - Hangzhou, Zhejiang, China