Polycystic Ovary Syndrome, Mitochondrial Dysfunction, Obesity, Insulin Resistance Infertility (POMODORI) Cohort
Recruiting · NCT06167135 · Observational (researchers observe without assigning treatment) · Lead sponsor: Semmelweis University
View the official record on ClinicalTrials.gov →What this trial is about
Enrolling of 150 female patients of fertile age diagnosed with PCOS, insulin resistance, infertility, or mitochondrial disease, and the same number of age- and sex-matched controls are planned. During the research biomarkers already with mitochondrial dysfunction in the scientific literature and common mtDNA abnormalities (deletions, point mutations, copy number changes, etc.) are examined.
Who can take part
Age range
20 Years to 45 Years
Sex
Female
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Presence of polycystic ovary syndrome (PCOS) or insulin resistance (IR) associated with other multisystemic phenotypes, mitochondrial dysfunction
- history of infertility associated with other multisystemic phenotypes, mitochondrial dysfunction
- a known history of mitochondrial dysfunction and PCOS and/or IR
- general health is good and there is no serious general medical condition that would prevent participation would make participation highly risky
Exclusion criteria
- poor cooperation
- refusal to participate in the study
Where it is running
1 location listed.
- Semmelweis University - Budapest, Hungary