Effect of Nitrate Supplementation on Blood Pressure and Microvascular Function of Resistant Hypertensive Patients
Recruiting · NCT06169241 · Interventional (participants receive a specific treatment) · Lead sponsor: National Institute of Cardiology, Laranjeiras, Brazil
View the official record on ClinicalTrials.gov →Interventions studied
Beetroot extractPlacebo
What this trial is about
Arterial hypertension (AH) has been identified as an important public health problem and considered a new epidemic with high mortality and morbidity. High blood pressure (BP) levels increase the chances of coronary artery disease (CAD), heart failure (HF), stroke, chronic renal failure (CRF) and death. Beetroot powder may be an easier way to increase the availability of nitric oxide and consequently vasodilation in these patients. However, studies are needed to evaluate its benefits in patients with AH.
Who can take part
Age range
18 Years to 75 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Early Phase 1
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Resistant hypertension, with a diagnosis described in the medical record, without changing medications or increasing doses in the last 30 days.
Exclusion criteria
- neoplasms
- heart failure
- use of medications with nitrate in their formula
- patients undergoing renal denervation
Where it is running
1 location listed.
- National Institute of Cardiology - Rio de Janeiro, Brazil