Incidence and Characterization of Drivers Oncogenes in the Population With Lung Cancer Afferents to the Cancer Institute in Aviano (IN.ON.D.)
Recruiting · NCT06180005 · Observational (researchers observe without assigning treatment) · Lead sponsor: Centro di Riferimento Oncologico - Aviano
View the official record on ClinicalTrials.gov →What this trial is about
According to an analysis by Memorial Sloan Kettering Cancer Center patients who receive a target therapy having an oncogenic driver mutation live longer than those who do not receive it. In addition to that, therapies guided by analysis on mutations identified in ct-DNA had a favorable impact, allowing longer survival. All this suggests that the presence of a therapeutically targetable oncogene (oncogene addicted) allows target therapy, resulting in a longer life expectancy. The main objective of this study is to evaluate the frequency of patients with oncogene addiction in a consecutive series of patients with NSCLC afferent to the CRO. Oncogene addiction is defined as being carriers of one of the mutations among EGFR, ALK, RET, KRAS, BRAF, Her2, ROS1, MET or other mutations that become therapeutic targets under investigation.
Who can take part
Inclusion criteria
- First visit or first admission to CRO occurred in the period from September 2023 to September 2028
- Diagnosis of NSCLC any stage
Exclusion criteria
- \- Diagnosis of tumor not of certain lung origin (uncertain origin)
Where it is running
1 location listed.
- Centro di Riferimento Oncologico (CRO) di Aviano - IRCCS - Aviano, Pordenone, Italy