LSM and SSM for the Diagnosis of CSPH: a Prospective Cohort Study
Recruiting · NCT06181409 · Observational (researchers observe without assigning treatment) · Lead sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre
View the official record on ClinicalTrials.gov →What this trial is about
The goal of this observational study is to assess non-invasive tools' efficacy in predicting portal hypertension-related complications in individuals with advanced chronic liver disease. The main question it aims to answer are: \- what are the cut-off values for non-invasive tests (NITs) (including LSM, SSM) that predict the presence and occurrence of hepatic decompensation in individuals with advanced chronic liver disease? Participants will undergo regular study visits involving non-invasive tests (LSM, SSM) and assessments to monitor hepatic decompensation over the study period.
Who can take part
Inclusion criteria
- Age above 18years old
- Advanced chronic liver disease (defined as LSM ≥ 10kPa)
- Ability to provide informed consent
Exclusion criteria
- Transjugular intrahepatic portosystemic shunt
- previous liver transplantation
- Abnormality of the porto-mesenteric system (portal vein thrombosis, splenic vein thrombosis, splenectomy, portal cavernomatous transformation, porto-caval shunts)
- Hematological malignancy
Where it is running
1 location listed.
- McGill University Health Centre - Montreal, Quebec, Canada