Cognitive Leisure and Preclinical Alzheimer's Disease: Exploring Neural Mechanisms
Recruiting · NCT06215274 · Observational (researchers observe without assigning treatment) · Lead sponsor: Yuanjiao Yan
View the official record on ClinicalTrials.gov →Interventions studied
Relationship of the cognitive leisure activity levels, cognitive function, and MRI characteristics.
What this trial is about
The goal of this clinical trial is aims to: 1. Translate and culturally adapt the Cognitive Leisure Activity Scale (CLAS) into Chinese and Conduct reliability and validity tests for the Chinese version of CLAS. 2. Investigate the correlation between cognitive leisure activity levels and cognitive function in the preclinical stage of Alzheimer's Disease (AD). 3. Clarify the regulatory mechanisms of cognitive leisure activity levels on the neural circuits of patients in the preclinical stage of AD.
Who can take part
Age range
60 Years and older
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Clinical diagnosis of Mild Cognitive Impairment (MCI) and Subjective Cognitive Decline (SCD)
- Age ≥ 60 years
- Capable of normal communication in Mandarin，possesses a certain level of comprehension and judgment.
Exclusion criteria
- Individuals with severe hearing or language impairments, or with severe physical illnesses that are unable to cooperate with the survey
- Individuals with pacemakers, metallic implants, cochlear implants, claustrophobia, and other contraindications for MRI examination.
Where it is running
1 location listed.
- Fujian Provincial Hospital - Fuzhou, Fujian, China