Short-term Effects of Preoperative Exercise in Moderate-to-high Perioperative Risk Lung Cancer Patients
Recruiting · NCT06215326 · Interventional (participants receive a specific treatment) · Lead sponsor: Guangdong Provincial People's Hospital
View the official record on ClinicalTrials.gov →Interventions studied
high-intensity interval trainingmoderate-intensity continuous training
What this trial is about
The goal of this clinical trail is to compare the effects of preoperative exercise training of different intensities on short-term cardiorespiratory function and postoperative outcomes in patients scheduled for lung resections.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Age\>18 years.
- Suspected or confirmed primary lung cancer with scheduled surgical treatment.
- Moderate-to-high perioperative risk, defined as FEV1\<60% of predicted value (wedge) or ppo FEV1\<60% of predicted value (lobectomy/segmentectomy) or VO2peak\<20 ml/kg/ min.
- Sign informed consent and accept to comply with the requirements of the study protocol.
- Completion of a baseline Complete cardiopulmonary exercise testing (CPET).
Exclusion criteria
- Concurrent or previous history of other malignant tumors.
- Life expectancy less than 1 year.
- Dementia; infirmity; or inability to participate in sports (musculoskeletal limitations, namely, injuries, frailty, and weakness).
- Inability to maintain exercise training.
- Irregular vital signs (heart rate: \< 40 or \> 120 bpm at rest; blood pressure: systolic blood pressure \> 200 mm Hg or diastolic pressure \> 110 mm Hg; T: ≥ 38.5 or ≤ 36◦C; SpO2 ≤ 90%).
- Currently enrolling in any other clinical trials.
- Patient refusal.
Where it is running
1 location listed.
- Guangdong Provincial People's Hospital - Guangzhou, Guangdong, China