Respiratory Muscle Fatigue and Lower Extremity Muscle Oxygenation
Recruiting · NCT06217276 · Interventional (participants receive a specific treatment) · Lead sponsor: Istanbul Medipol University Hospital
View the official record on ClinicalTrials.gov →Interventions studied
Respiratory muscle fatigue protocol
What this trial is about
In our study, changes in vastus lateralis muscle oxygenation will be evaluated with the Moxy device, a functional infrared oxygen measurement device, during the inspiratory muscle fatigue protocol in COPD cases and the healthy control group.
Who can take part
Age range
18 Years to 75 Years
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Having a diagnosis of Stage 2-3 COPD according to the following clinical diagnostic criteria according to the American Thoracic and European Respiratory Societies (ATS-ERS).
- Having been using the same medications for the last 4 weeks
Exclusion criteria
- Patients with severe comorbid diseases, unstable coronary artery disease, collagen vascular diseases and requiring high-flow oxygen therapy (˃ 3-4 L\\min).
- Presence of any vascular problem that may affect lower extremity muscle oxygenation
- Presence of another respiratory system disease other than COPD
- Patients who have had an acute COPD exacerbation in the last 4 weeks
- Patients experiencing COPD exacerbations during the study protocol
- Presence of fatty tissue or scar tissue at the measurement points, which may impair the measurement quality.
- Have already participated in another clinical trial within the last 30 days that may affect the results of the study.
- Inclusion Criteria for Healthy Cases
- Being over 18 years of age
- Not having any diagnosed chronic disease
- Not being a smoker
Where it is running
1 location listed.
- Yedikule Chest Disease Hospital - Istanbul, Zeytinburnu, Turkey (Türkiye)