A Clinical Study to Map the HLA Genomic Region in the Greek Population
Recruiting · NCT06227468 · Observational (researchers observe without assigning treatment) · Lead sponsor: Athens LifeTech Park
View the official record on ClinicalTrials.gov →What this trial is about
The aim of GENESIS clinical study is to map the HLA genomic region in the Greek population and evaluate possible correlations with selected underlying diseases.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- The study will include adult subjects (age ≥ 18) that:
- possess a Greek social security number and are visiting hospitals/clinics, and/or other private laboratory institutions (incl. clinics and health care groups) as part of standard clinical practice in Greece,
- are willing and able to provide written informed consent to participate in the study according to the study protocol.
Exclusion criteria
- Subjects not able to provide written informed consent (e.g. ICU patients, mental illness patients, lack of legal capacity).
- Subjects who have had an allogeneic (non-self-donor):
- bone marrow transplant
- stem cell transplant
- blood transfusion less than two weeks prior to buccal swab sample collection
- liver transplant
- Subjects who participated in an interventional clinical trial in the past that according to the subject's physician opinion might have had an impact on their HLA genome.
Where it is running
8 locations listed.
- Department of Infectious Diseases, 2nd Department of Internal Medicine, University General Hospital of Alexandroupolis - Alexandroupoli, Greece
- Department of Cardiology, University General Hospital of Heraklion - Heraklion, Greece
- Department of Rheumatology, University Hospital of Heraklion - Heraklion, Greece
- Department of Respiratory, University Hospital of Ioannina - Ioannina, Greece
- Department of Haematology, University General Hospital of Larissa - Larissa, Greece
- 2nd Propaedeutic Department of Internal Medicine, Attikon University General Hospital - Chaïdári, Attica, Greece
- 2nd Department of Neurology, AHEPA University Hospital - Thessaloniki, Thessaloniki, Greece
- Department of Respiratory Medicine, University General Hospital of Alexandroupolis - Alexandroupoli, Thrace, Greece