A Study of RAY1225 in Participants With Obesity
Recruiting · NCT06254261 · Interventional (participants receive a specific treatment)
View the official record on ClinicalTrials.gov →Interventions studied
PlaceboRAY1225
What this trial is about
The main purpose of this study is to learn more about the Tolerability of RAY1225 in participants with Obesity. The study will also explore the efficacy of RAY1225. The study will last about six months for each participant.
Who can take part
Age range
18 Years to 70 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Phase 2
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Have a body mass index (BMI) of ≥28 kilogram per square meter (kg/m²) or ≥24 kg/m² and previously diagnosed with at least one of the following weight related comorbidities: hypertension, dyslipidemia, obstructive sleep apnea, fatty liver disease,or HbA1c ≥5.7% and \< 6.5%;
- Participants (including partners) must use reliable methods of contraception during the study and until 6 months following the last dose of investigational product.
Exclusion criteria
- Obesity induced by other endocrinologic disorders or monogenetic or syndromic forms of obesity
- with a history of diabetes or hypoglycemia;
- Have a family or personal history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia (MEN) Syndrome type 2 or with thyroid nodules of unknown etiology found at screening and considered clinically significant by the investigator.
- Have a prior or planned surgical treatment for obesity (excluding liposuction or abdominoplasty if performed \>1 year prior to screening)
- allergic constitution;
- not suitable for subcutaneous injection.
Where it is running
1 location listed.
- Peking University People's Hospital - Beijingcun, Hebei, China