Green Propolis Extract and Royal Jelly in Hypertensive Patients and/or With Chronic Kidney Disease
Recruiting · NCT06288204 · Interventional (participants receive a specific treatment) · Lead sponsor: Universidade Federal Fluminense
View the official record on ClinicalTrials.gov →Interventions studied
PlaceboPropolis associated with Royal JellyRoyal Jelly
What this trial is about
This work aims to evaluate the effects of the association of green propolis extract with royal jelly on inflammation and oxidative stress in participants with chronic kidney diseases (CKD) and Systemic arterial hypertension (SAH), in a longitudinal, randomized, double-blind, placebo-controlled clinical trial that will be carried out for 2 months.
Who can take part
Age range
18 Years to 75 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- patients in stages 3 and 5 of CKD (GFR from 15 to 59 mL/min),
- patients receiving ambulatorial nutrition treatment at least 6 months
- patients on regular Hemodialysis treatment for at least 6 months
- patients using one to three antihypertensive drugs
Exclusion criteria
- autoimmune and infectious diseases,
- diabetes
- cancer
- AIDS
- pregnant women
- patients using catabolic drugs or antibiotics;
- patients with catheter access to hemodialysis;
- patients using antioxidant vitamin supplements, prebiotics, probiotics, symbiotic,
- Patients on regular intake of propolis who are allergic to corn starch or report being allergic to bee stings.
- patients with acute myocardial infarction (AMI) and/or cerebrovascular accident (CVA)
Where it is running
2 locations listed.
- Denise Mafra - Rio de Janeiro, Rio de Janeiro, Brazil
- Denise Mafra - Rio de Janeiro, Rio de Janeiro, Brazil