Provocative Tests for HFpEF
Recruiting · NCT06309550 · Observational (researchers observe without assigning treatment) · Lead sponsor: Istituto Auxologico Italiano
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
Diagnosing heart failure with preserved ejection fraction (HFpEF) in patients complaining exertional breathlessness can be challenging: diagnostic algorithms and scores have low sensitivity, and ageing-associated comorbidities can complicate the interpretation of symptoms. Thus, exercise right heart catheterization (RHC) or invasive cardiopulmonary exercise test (iCPET) have been advocated as gold-standard methods for HFpEF diagnosis. However, exercise RHC and iCPET are still not widely standardized methods, with results mainly coming from US cohorts (that may differ from Italian cohorts), and other provocative tests (e.g. non-invasive CPET, passive leg raising) may offer complementary diagnostic information.
Who can take part
Inclusion criteria
- dyspnea
Exclusion criteria
- known HFpEF
Where it is running
1 location listed.
- Ospedale San Luca IRCCS Istituto Auxologico Italiano - Milan, Italy