Effect of CPAP Treatment in Patients With Severe Uncontrolled Asthma: The ASTHMA-SLEEP Trial
Recruiting · NCT06314477 · Interventional (participants receive a specific treatment) · Lead sponsor: Hospital Clinic of Barcelona
View the official record on ClinicalTrials.gov →Interventions studied
CPAP treatmentHygienic and dietary advice
What this trial is about
The aim of the study is to evaluate the impact of CPAP treatment on asthma control in patients with severe uncontrolled asthma and obstructive sleep apnea (OSA)
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Age \>18 years
- Diagnosis of severe uncontrolled asthma according to the criteria of the Spanish Asthma Management Guide (GEMA) or the Global Initiative for Asthma (GINA) and no hospitalizations the month prior to inclusion in the study.
- Apnea hypopnea rate greater than or equal to 15/hour
- Punctuation in the Epworth Sleepiness Scale ≤10
- Obtaining informed consent.
Exclusion criteria
- Previous treatment with CPAP
- Patient with central sleep apnea or Cheyne-Stokes respiration
- Other sleep disorders: narcolepsy, restless leg syndrome, chronic insomnia,
- Resistant hypertension
- Active Smoking
- Unstable comorbidities or medications may interfere with asthma control
- Pregnancy
- Any process that reduces life expectancy to \<1 year,
- Any medical or social factor that may limit CPAP compliance
Where it is running
1 location listed.
- Hospital Clinic Barcelona - Barcelona, Spain, Spain