Ultrasound-guided Stellate Ganglion Block for Treatment of Chronic Migraine in Adult
Recruiting · NCT06322407 · Interventional (participants receive a specific treatment) · Lead sponsor: Beijing Tiantan Hospital
View the official record on ClinicalTrials.gov →Interventions studied
Stellate Ganglion Block (SGB)standardized drug treatment
What this trial is about
To assess the 6-months effects and safety of stellate ganglion block(SGB) for Chronic Migraine (CM) patients who failure to undergo preventive therapy and are seeking a more suitable non-pharmacological therapy.
Who can take part
Age range
18 Years to 65 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Age from 18 to 65 years;
- Diagnosed with CM according to the International Classification of Headache Disorders, 3rd (ICHD-3) criteria \[Headache Classification Committee of the International Headache Society (IHS). The International Classification of Headache Disorders, 3rd edition. Cephalalgia. 2018;38:1-211\].
- not received prior prophylactic migraine treatment or, due to lack of efficacy or tolerability, had failed or had not been suitable for up to three previous prophylactic treatments from the following: Metoprolol/propranolol, amitriptyline, and flunarizine.
Exclusion criteria
- BMI \<15 kg/m2 or \>35 kg/m2；
- Previous SGB treatment；
- History of other neurological disorders；
- History of severe cardiopulmonary, hepatic or renal dysfunction；
- History of allergies to any of the study drugs；
- Patients with chronic use of opioids；
- Preoperative coagulation abnormalities (activated partial thromboplastin time greater than 1.5 time normal value)；
- Infection or mass near the puncture site；
- Neck anatomic structural changes (caused by radiotherapy or surgery);
- Pregnant or breast feeding;
- Psychological disorders;
- Refusal to sign informed consent.
Where it is running
1 location listed.
- Beijing Tiantan Hospital - Beijing, Beijing Municipality, China