Neurofilament Light Chain And Voice Acoustic Analyses In Dementia Diagnosis
Recruiting · NCT06339190 · Observational (researchers observe without assigning treatment) · Lead sponsor: Monash University
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
This cohort study aims to determine if a blood test can aid with diagnosing dementia in anyone presenting with cognitive complaints to a single healthcare network. The investigators will measure levels of a brain protein, Neurofilament light chain (Nfl), and assess changes in language using speech tests. Participants will have a single blood test and speech test, and will be followed up at 12-months to complete questionnaires and cognitive scales over the phone. The speech test will also be completed again at 12-months. Individuals at risk of a Fronto-temporal dementia syndrome will be eligible to complete optional genetic testing involving an 'at home' saliva sample.
Who can take part
Inclusion criteria
- All patients presenting to Eastern Health services with a cognitive complaint or potential neurodegenerative disorder
Exclusion criteria
- Prognosis \<12 months
- No cognitive complaint
- Patients not involved within the single healthcare network
Where it is running
2 locations listed.
- Box Hill Hospital - Box Hill, Victoria, Australia
- Wantirna Health - Wantirna, Victoria, Australia