Tenofovir Disoproxil Fumarate in the Treatment of Parkinson's Disease
Recruiting · NCT06356662 · Interventional (participants receive a specific treatment) · Lead sponsor: The Fourth Affiliated Hospital of Zhejiang University School of Medicine
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
To evaluate the efficacy and safety of tenofovir disoproxil fumarate in the treatment of Parkinson's disease. The changes of motor symptoms and the occurrence of adverse reactions in early Parkinson's disease patients who took tenofovir disoproxil fumarate and did not take Tenofovir disoproxil fumarate at different time points were compared.
Who can take part
Age range
18 Years to 65 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Phase 1
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- 1: Parkinson's disease: Hoehn Yahr= 1 to 2.5 2: MMSE score≥24
Exclusion criteria
- 1: essential tremor, stroke, epilepsy and other well-defined neurological disorders
- : Or have received deep brain stimulation and other brain surgery
- : Abnormal liver and kidney function
- : Infected with chronic hepatitis B or AIDS (HIV-1 infection)
- : Severe depression, schizophrenia, other psychiatric disorders or drug dependence
- : Other serious physical diseases such as heart, lung, liver, kidney disease, blood disease and malignant tumor
- : Pregnant or lactating women and seniors over 65 years of age
- : Allergy or other contraindications to the investigational drug
Where it is running
1 location listed.
- Guohua Zhao - Hangzhou, Zhejiang, China