Resistance Training and Corticospinal Excitability in Multiple Sclerosis
Recruiting · NCT06374108 · Interventional (participants receive a specific treatment) · Lead sponsor: University of Aarhus
View the official record on ClinicalTrials.gov →Interventions studied
Progressive resistance training
What this trial is about
The goal of the present study is to investigate effects of progressive resistance training on central nervous system functioning (corticospinal excitability (CSE)) and walking capacity in persons with multiple sclerosis (pwMS). A total of 54 pwMS will be enrolled and randomized into 1 of 3 groups: high dose resistant training (RT), low dose RT, and waitlist control.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Age ≥ 18 years
- MS diagnosis according to the McDonald diagnostic criteria
- Shows impairments in walking capacity
- Ability to self transport to test and exercise
Exclusion criteria
- Pregnancy
- Neurological or other comorbidities that affects the nervous system
- Relapse within the past 2 months
- Pacemaker or metallic implants
- Hypertension (medically unregulated)
- Participation in structured RT over the past 3 months (≥ 2 sessions/week).
Where it is running
2 locations listed.
- Department of Public Health - Aarhus, Central Jutland, Denmark
- Department of Nutrition, Exercise and Sports, University of Copenhagen - Copenhagen, Copenhagen N, Denmark