Effect of Lidocaine on Postoperative Pain and Long-term Survival in Elderly Patients Undergoing Colorectal Surgery
Recruiting · NCT06405776 · Interventional (participants receive a specific treatment) · Lead sponsor: West China Hospital
View the official record on ClinicalTrials.gov →Interventions studied
Placebolidocaine
What this trial is about
This study is a further observation and follow-up of the patients enrolled in the registration number NCT05920980 to further evaluate the effect of long-term infusion of lidocaine on postoperative chronic pain, long-term quality of life and survival rate in patients undergoing colorectal cancer surgery.
Who can take part
Age range
60 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Participants were at least 60 years old;
- American Society of Anesthesiologists (ASA) physical status I to III;
- Body-mass index of 18-30 kg/m2;
- Scheduled for elective colorectal surgery.
Exclusion criteria
- Metastases occurring in other distant organs;
- Severe hepatic insufficiency (aspartate aminotransferase or alaninetransaminase or bilirubin \>2.5 times the upper limit of normal);
- Renal impairment (creatinine clearance \<60 mL/min);
- Cardiac rhythm disorders or systolic heart failure (second-and thirddegree heart block, ejection fraction \<50%);
- Allergies to any of the trial drugs; chronic opioid use;
- Inability to comprehend numeric rating scale.
Where it is running
1 location listed.
- China - Sichuan, China