Prehabilitation for EOC, Fallopian Tube, Primary Peritoneal Carcinoma and Pancreatic Cancer w/ NACT
Recruiting · NCT06412510 · Interventional (participants receive a specific treatment) · Lead sponsor: Case Comprehensive Cancer Center
View the official record on ClinicalTrials.gov →Interventions studied
Prehabilitation
What this trial is about
The purpose of this study is to see whether participants who are assigned to a multimodal prehabilitation intervention during chemotherapy are able to adhere with exercise and nutrition program to prepare for their cancer surgery.
Who can take part
Age range
65 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Phase 1, Phase 2
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Age 65 and older
- Patients with diagnosis of advanced (Stage III or IV) epithelial ovarian, fallopian tube, or
- Patients with diagnosis of pancreatic adenocarcinoma (PDAC) (Stage I, II, or III) undergoing neoadjuvant chemotherapy.
- Patients with locally advanced esophageal cancer undergoing neoadjuvant chemotherapy.
- Patients with locally advanced muscle invasive bladder cancer undergoing neoadjuvant chemotherapy.
Exclusion criteria
- Life expectancy less than 3 months in the opinion of the treating physician
- Patients unable to provide informed consent.
- Wheelchair bound patients/ physical immobility.
- Severe cardiopulmonary disease defined as NYHA class III or IV
- Patients with malignant bowel obstruction who will require surgical intervention or nutritional support in the form of enteral or parenteral nutrition will also be excluded.
- Patients with any other comorbidity or condition, which, in the opinion of the enrolling investigator, would place the patient at unnecessarily higher greater risk or burden, or participating in the study would not be in the best interests of the patient.
Where it is running
1 location listed across 1 US state.
- Cleveland Clinic Taussig Cancer institute, Case Comprehensive Cancer Center - Cleveland, Ohio, United States