Risk Factors for Non-response to Hormonal Medical Therapy in Patients With Endometriosis
Recruiting · NCT06413381 · Observational (researchers observe without assigning treatment) · Lead sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna
View the official record on ClinicalTrials.gov →What this trial is about
Determine the proportion of patients with endometriosis unresponsive to medical therapy and to compare the clinical and ultrasonographic characteristics of this group of patients (study group) with the clinical and ultrasonographic characteristics of patients responsive to medical therapy (control group).
Who can take part
Age range
18 Years to 50 Years
Sex
Female
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- age between 18 and 50 years;
- patients with endometriosis-related pain symptoms (dyspareunia, dyschezia, dysmenorrhea, chronic pelvic pain, dysuria, periovulatory pain, with at least one of these symptoms presenting Numerical Pain Rating Scale intensity \> 5);
- indication for administration of oral hormonal medical treatment for endometriosis;
- acquisition of informed consent.
Exclusion criteria
- patients with contraindications to oral hormone treatment
- current or previous pelvic infections
- history of malignancy or current suspicion of gynecologic malignant lesions
- previous pelvic surgery (hysterectomy, salpingectomy, ovarian cyst removal, myomectomy, surgery for endometriosis, bowel resections)
- positive history of other causes of chronic pelvic pain
- post-menopausal status
Where it is running
1 location listed.
- IRCCS Azienda Ospedaliero-Universitaria, Policlinico Sant'Orsola - Bologna, BO, Italy