A Translational Study to Describe Clinical Characteristics, Biomarkers and to Identify Phenotypes and Endotypes Associated With Differential Outcomes in Chinese Population
Recruiting · NCT06419413 · Observational (researchers observe without assigning treatment) · Lead sponsor: AstraZeneca
View the official record on ClinicalTrials.gov →What this trial is about
A Translational Study to Describe Asthma Patient Clinical Characteristics, Treatment Patterns, Biomarkers and to Identify Phenotypes and Endotypes associated with Differential Outcomes that may Support Future Development of Personalised Treatment Strategies in Chinese Population
Who can take part
Age range
18 Years to 75 Years
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Age 18 to 75 years of age
- acceptable FEV1 (according to ATS and ERS)
- compliance with study procedures All Asthma Cohorts
- physician diagnosed Asthma greater or equal to 3 months prior to screening visit
Exclusion criteria
- history of alcohol or drug abuse within the past year
- pregnant at time of an assessment
- has an altered mental status at the time of informed consent
- receipt marketed or investigational biologic(s) within 3 months or 5 half-lives prior to visit 1, whichever is longer
- history or current upper or lower respiratory infection or symptoms within 2 weeks of baseline assessments
- terminal diseases and/or organ failure or participants otherwise considered not appropriate for the study participation
- Receipt LTRAs or 5-lipoxygenase (5-LO) inhibitors (eg zileuton and montelukast) within 1 month or 5 half-lives prior to baseline, whichever is longer.
Where it is running
21 locations listed.
- Research Site - Beijing, China
- Research Site - Changsha, China
- Research Site - Dongguan, China
- Research Site - Foshan, China
- Research Site - Guangzhou, China
- Research Site - Hainan, China
- Research Site - Hohhot, China
- Research Site - Huizhou, China
- Research Site - Kunming, China
- Research Site - Nanjing, China
- Research Site - Nanning, China
- Research Site - Shanghai, China
- Research Site - Shenyang, China
- Research Site - Taiyuan, China
- Research Site - Wenzhou, China
- Research Site - Wuhan, China
- Research Site - Xi'an, China
- Research Site - Xuzhou, China
- Research Site - Zhanjiang, China
- Research Site - Zhaoqing, China
- Research Site - Chengdu, Sichuan, China