Effect of Resistance Training in Patients on the Waiting List for Heart Transplant
Recruiting · NCT06426173 · Interventional (participants receive a specific treatment) · Lead sponsor: University of Sao Paulo General Hospital
View the official record on ClinicalTrials.gov →Interventions studied
Resistance Training ProgramStandard Treatment Group
What this trial is about
The present longitudinal, randomized, and blinded clinical trial aims to: * Evaluate the effects of resistance training on the functional capacity, quality of life, and cardiac biomarkers of hospitalized patients with heart failure (HF) on the waiting list for heart transplantation (HTx). * Evaluate the associations between Fried's frailty classification and functional capacity responses to resistance training. The protocol will have a total duration of 12 weeks.
Who can take part
Age range
18 Years to 70 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- patients included in heart transplant list ≤1 month
- hemodynamically stable in the last 48 hours defined as mean arterial pressure (MAP) ≥ 60 mmHg and ≤ 120 mmHg and - Heart rate (HR) ≥ 60 bpm and ≤ 120 mmHg.
- dobutamine dose ≤ 10 mcg/kg/min
Exclusion criteria
- heart failure of arrhythmogenic and/or restrictive etiology
- presence of uncontrolled acute arrhythmias
- cognitive, orthopedic, or neuromotor changes that prevent functional tests from being carried out
Where it is running
1 location listed.
- Instituto do Coração - Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo - São Paulo, São Paulo, Brazil