Quality of Life in Patients Transitioning to Home or In-Center Dialysis (QUALIFY CKD-to-HOME)
Recruiting · NCT06458322 · Observational (researchers observe without assigning treatment) · Lead sponsor: Ciusss de L'Est de l'Île de Montréal
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
The goal of this study is to evaluate quality of life (QoL) and frailty trajectories from advanced chronic kidney disease (CKD) to after dialysis initiation, specifically comparing patients choosing home dialysis and in-center hemodialysis. The main questions it aims to answer are: 1. What is the trajectory of QoL in patients transitioning from advanced CKD to dialysis (up to 12 months after initiation) and how does these changes differ for patients oriented towards home dialysis and in-center hemodialysis? 2. Is the development of frailty after dialysis initiation less likely in patient pursuing home dialysis? 3. What is the variation in other PROMs and health outcomes (fatigue, anxiety \& depression, general assessment, cognitive function) form advanced CKD to the first 12 months after dialysis initiation? 4. What are the predictors of severe decline in QoL, frailty and other important health outcomes (fatigue, cognition, anxiety \& depression) during CKD G5 follow-up and after 12 months post dialysis initiation? Participants will be ask to: * Answer some questions and complete questionnaires each 3 months; * Do a a grip test and a walking test each 6 months to evaluate their frailty;
Who can take part
Inclusion criteria
- Adult patients followed in advanced CKD clinic;
- eGFR ≤12 mL/min/1.73m2 96;
- Understand English or French.
Exclusion criteria
- Orientation toward conservative treatment;
- Planned kidney transplantation \< 6 months;
- Unable to provide consent due to severe cognitive or psychiatric disease;
- Previous treatment with dialysis \> 3 month;
- Life expectancy \< 6 months.
Where it is running
1 location listed.
- Hôpital Maisonneuve-Rosemont - Montreal, Quebec, Canada