Impact of Combined Oral Contraceptive Pills on Migraine
Recruiting · NCT06509503 · Interventional (participants receive a specific treatment) · Lead sponsor: Kafrelsheikh University
View the official record on ClinicalTrials.gov →Interventions studied
Combined oral contraceptiveVaginal Ring
What this trial is about
The investigators will assess the effect of combined oral contraceptive pills (COCs) on migraine features and treatment response to allow better interpretation of the exact consequence of hormonal contraceptive use on migraineurs.
Who can take part
Age range
18 Years to 55 Years
Sex
Female
Healthy volunteers
No - a diagnosis or condition is required
Phase
Phase 4
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- female migraine patients on COCs or mechanical contraceptive methods, according to the International Classification of Headache Disorders 3rd edition, aged 18-55 years
Exclusion criteria
- Patients with major neurological conditions such as (epilepsy, ischemic or hemorrhagic stroke, multiple sclerosis, mitochondrial diseases, and brain tumors).
- pregnant, lactating, and menopausal patients.
- Patients with any contraindications to ibuprofen or propranolol.
Where it is running
1 location listed.
- Kafr Elsheikh University Hospital - Kafr ash Shaykh, Egypt