Identification of Multiple Pulmonary Diseases Using Volatile Organic Compounds Biomarkers in Human Exhaled Breath
Recruiting · NCT06528418 · Observational (researchers observe without assigning treatment) · Lead sponsor: ChromX Health
View the official record on ClinicalTrials.gov →Interventions studied
Gas chromatography-mass spectrometry(GC-MS) and micro Gas Chromatography-photoionisation detector (μGC-PID) system
What this trial is about
The goal of this observational study is to develop an advanced expiratory algorithm model utilizing exhaled breath volatile organic compound (VOC) marker molecules. This model aims to accurately diagnose mutiple pulmonary diseases. The primary objectives it strives to accomplish are: 1. To assess the diagnostic accuracy of an exhaled breath VOC-assisted diagnostic artificial intelligence (AI) model in diagnose several common pulmonary diseases. 2. To assess the diagnostic accuracy of an exhaled breath VOC-assisted diagnostic artificial intelligence (AI) model in diagnose more pulmonary diseases.
Who can take part
Age range
18 Years to 100 Years
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Males or females, age must be 18 years old or above.
- Patients must meet the CT imaging diagnostic criteria for different lung diseases, and patients must be able to provide electronic versions of CT image data.
- Patients must have a clear clinical diagnosis.
- All participants must sign a written informed consent form.
Exclusion criteria
- Pregnant women.
- Individuals with a history of cancer other than lung disease.
- Individuals who have undergone organ transplants or non-autologous (allogeneic) bone marrow or stem cell transplants.
- Individuals with other severe organic diseases or mental illnesses.
- Individuals with metabolic diseases such as diabetes, hyperlipidemia, etc.
- Any other condition that researchers deem unsuitable for participation in this clinical trial.
Where it is running
2 locations listed.
- The First Affiliated Hospital of Guangzhou Medical University - Guangzhou, Guangdong, China
- The First Affiliated Hospital of Guangzhou Medical University - Guangzhou, Guangdong, China