Effects of Resistance Training Intensity on Cardiovascular Parameters of Hypertensive Women
Recruiting · NCT06538454 · Interventional (participants receive a specific treatment) · Lead sponsor: University of Sao Paulo
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
The goal of this clinical trial is to understand about the effects of resistance training (RT) intensity on cardiovascular parameters in postmenopausal women with systemic arterial hypertension (SAH). The main research questions are: * Does the intensity of RT impact blood pressure (BP) in postmenopausal women with SAH? * How does RT intensity affect heart rate (HR) and their variability (HRV), endothelial function (EF), and nitric oxide (NO) biomarker synthesis in this population? * What are the effects of RT intensity on affectivity and rate of perceived exertion (RPE)? Researchers will compare two different intensities of RT (60% of the load for 1 repetition maximum \[1RM\] and 80% of 1RM) to determine their effects on the mentioned cardiovascular and perceptual parameters. Participants will: In the acute experiment: * Perform the same RT session in a crossover design, training with 60% of 1RM in one condition and 80% of 1RM in another condition * Have BP, HR, and HRV measured before, immediately after, and for one hour post-session * Report affectivity before each session and at the end, along with RPE In the chronic experiment: * Be randomized into two groups: one training with 60% of 1RM and the other with 80% of 1RM * Undergo a 10-week intervention period with evaluations before, during, and after the intervention * Have BP, HR, affective responses, and RPE measured at multiple time points * Have EF, HRV, and salivary concentrations of NO biomarkers assessed before and after the intervention
Who can take part
Inclusion criteria
- Women with 50 to 65 old years;
- Postmenopausal diagnosis (amenorrhea for 12 months or more);
- Previous diagnosis of hypertension and treat with medications;
- Physically inactive.
Exclusion criteria
- History of other cardiovascular problems (heart failure, heart attack, stroke, etc);
- Grade II obesity (BMI ≥ 35 kg/m²);
- Medications (beta-blockers and/or non-dihydropyridine calcium channel blockers);
- Systolic blood pressure at rest above 160 mmHg and/or dyastolic blood presure above 105 mmHg;
- Unable to perform resistance exercise due to musculoskeletal or cognitive reasons.
Where it is running
1 location listed.
- Laboratório de Fisiologia do Exercício e Metabolismo - Ribeirão Preto, São Paulo, Brazil