Consistency of LGE-MRI Fibrosis and EAM Low-voltage Area
Recruiting · NCT06552845 · Observational (researchers observe without assigning treatment) · Lead sponsor: China National Center for Cardiovascular Diseases
View the official record on ClinicalTrials.gov →Interventions studied
LGE-MRI Scan
What this trial is about
This study aims to: 1. Assess the consistency of LGE-MRI bi-atrial fibrosis and electroanatomical mapping of bi-atrial low voltage region 2. To evaluate the electroanatomical characteristics of different types of fibrosis (dense fibrosis, patchy fibrosis, etc.) in different locations of the left and right atrium; 3. To explore the correlation between preoperative and postoperative bi-atrial fibrosis and long-term recurrence in patients with atrial fibrillation.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Adult patients (≥18 years old) who are willing to participate in this study and can sign informed consent;
- Atrial fibrillation was diagnosed and catheter ablation was proposed
Exclusion criteria
- Left atrial thrombus or left atrial appendage thrombus;
- Severe chronic obstructive pulmonary disease (FEV1/ FVC\<70%, FEV1\<50% predicted value);
- Absolute contraindications of anticoagulation therapy;
- Currently pregnant;
- Contraindications for LGE-MRI (claustrophobia, pacemaker implantation, eGFR\<30ml/min for renal insufficiency, severe obesity, pregnancy, gadolinium chelating agent allergy, etc.);
- refuse to participate in the study;
- other physical or mental incapacity to participate in the study.
Where it is running
1 location listed.
- Fuwai Hospital, CAMS&PUMC - Beijing, Beijing Municipality, China