Physiologic Effects of Nasal High Flow on Exercise Tolerance in COPD
Recruiting · NCT06578156 · Interventional (participants receive a specific treatment) · Lead sponsor: University of Miami
View the official record on ClinicalTrials.gov →Interventions studied
Nasal High Flow CannulaNasal Low Flow Cannula
What this trial is about
This study aims to assess whether to describe the effects of the administration of nasal high flow (NHF) at 70 liters per minute (L/min) in a 6-Minute Walk Test (6-MWT) among Chronic Obstructive Pulmonary Disease (COPD) patients and to characterize the association between self-reported dyspnea with and without NHF at 70 L/min following a 6-MWT.
Who can take part
Age range
18 Years to 100 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Able to consent
- Age 18 years or older
- Diagnosis of COPD
- Ability to ambulate without assistance
- Use of low-flow nasal cannula ≤ 4 L/min or no supplemental oxygen (O2) at all
Exclusion criteria
- Pregnancy
- Being on bedrest
- Inability to consent or cooperate with the study
- Using of \> 4 L/min of supplemental O2 or requiring non-invasive ventilation during the daytime
- Hemodynamic instability (resting heart rate \> 130/minute, systolic blood pressure of ≤ 90 mmHg or ≥ 180 mmHg)
- Metal implants in the thoracic regions (pacemakers, Automatic Implantable Cardioverter Defibrillator (AICD), plates, screws, rods, and disc replacements)
Where it is running
1 location listed across 1 US state.
- University of Miami - Miami, Florida, United States