Understanding the Transition from Normal Melanocytes to Nevus to Melanoma
Recruiting · NCT06605417 · Observational (researchers observe without assigning treatment) · Lead sponsor: Fundacion Clinic per a la Recerca Biomédica
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
The primary objective of this study is to identify the molecular identity profiles of all cellular states that characterize the progression from benign nevi to malignant melanoma in CAYA patients with L/GCMN. The secondary objectives are: * To longitudinally characterize the cell-free DNA (cfDNA) from CAYA patients. * To improve the early diagnosis and treatments for intermediate conditions such as L/GCMN through evidence-based interpretation of personal risk from endogenous or exogenous sources. * To test pre-clinical strategies to best model and improve patient response.
Who can take part
Age range
No age limits stated
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Congenital nevus with estimated size of 20 cm
- Be over 18 years of age
Exclusion criteria
- No available biological material
- Not having signed the informed consent
Where it is running
2 locations listed.
- Hospital Clínic de Barcelona (Dermatology service) - Barcelona, Spain
- French National Institute of Health and Medical Research - Marseille, France