PrEP Readiness Interventions for Sustained Motivation (PRISM)
Recruiting · NCT06637436 · Interventional (participants receive a specific treatment) · Lead sponsor: Florida International University
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
This is a hybrid type I randomized controlled trial to test the effectiveness of contingency management (CM) alone versus CM with motivational interviewing (MI) for optimizing entry or re-entry into the HIV prevention or care continua. A total of 400 participants will be randomized to CM (n = 200) or MI+CM (n = 200), all delivered via telehealth. Monthly follow-up assessments will be completed over 12 months to examine effectiveness MI+CM for the primary outcome - filling a pre-exposure prophylaxis (PrEP) or anti-retroviral therapy (ART) prescription (verified using a digital photo). Secondary outcomes will include: self-reported PrEP or ART clinical evaluation by a provider; self-reported meth and other substance use severity (ASSIST), and self-reported receptive and insertive condomless anal sex (CAS).
Who can take part
Inclusion criteria
- 18 years or older
- Assigned male a birth
- Self-reported methamphetamine use in the past 3 months
- HIV-negative or unknown serostatus at baseline
- Has not filled a PrEP prescription in the past 6 months
Exclusion criteria
- Unwilling or unable to provide informed consent
Where it is running
1 location listed across 1 US state.
- Florida International University - Miami, Florida, United States