A Pragmatic Trial Comparing Empagliflozin and Dapagliflozin Through Cluster Randomization Embedded in the Electronic Health Record
Recruiting · NCT06642272 · Interventional (participants receive a specific treatment) · Lead sponsor: Herlev and Gentofte Hospital
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
The aim of this clinical trial is investigate the comparative effectiveness of empagliflozin and dapagliflozin for the treatment of diabetes, chronic kidney disease, and heart failure. Patients who are prescribed either empagliflozin or dapagliflozin, as part of daily clinical practice at the participating sites, will be included in the study. Treatment will be randomized automatically through the electronic health record software in clusters defined by time of day. https://www.appletreestudy.com
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Phase 4
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Adults aged 18 years or more
Exclusion criteria
- Incapabability of giving informed consent
- Withdrawal of informed consent
Where it is running
12 locations listed.
- Bispebjerg Hospital - Copenhagen, Denmark
- Rigshospitalet - Copenhagen, Denmark
- Herlev and Gentofte Hospital - Herlev, Denmark
- Steno Diabetes Center Copenhagen - Herlev, Denmark
- Nordsjællands Hospital - Hillerød, Denmark
- Holbæk Sygehus - Holbæk, Denmark
- Hvidovre Hospital - Hvidovre, Denmark
- Sjællands Universitetshospital - Køge, Denmark
- Nykøbing F. Sygehus - Nykøbing Falster, Denmark
- Sjællands Universitetshospital - Roskilde, Denmark
- Bornholms Hospital - Rønne, Denmark
- Slagelse Sygehus - Slagelse, Denmark