Using FAPI PET/MRI to Evaluate Prostate Cancer
Recruiting · NCT06675357 · Interventional (participants receive a specific treatment) · Lead sponsor: University of Wisconsin, Madison
View the official record on ClinicalTrials.gov →Interventions studied
FAPIMagnetic Resonance ImagingPositron Emission Tomography (PET)
What this trial is about
The goal of this clinical trial is to gain more information about how FAPI (fibroblast activation protein inhibitor) binds to certain type of cells in the tumor tissue. The main question it aims to answer is how this information can be used to better diagnose and track prostate cancer. Participants will undergo two PET/MRI scans during two research visits, each of which may last up to 2.5 hours.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Phase 2
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Age 18 years or older
- Able and willing to provide informed consent
- Known diagnosis of prostate cancer
- Scheduled for or recently performed (within 4 weeks) standard-of-care PSMA PET
- Optional: Scheduled for SOC biopsy of an established or suspected non-osseous, non-nodal metastases.
- Willing and able to undergo PET/MRI as part of this research
Exclusion criteria
- Unable or unwilling to provide informed consent
- Contraindication(s) to or inability to undergo PET/MRI
- Participants for whom PET/MRI will delay timely delivery of treatment
- Participants requiring intravenous (IV) conscious sedation for imaging care; those requiring mild, oral anxiolytics for the clinical MRI will be allowed to participate as long as the following criteria are met:
- Have their own prescription for the medication
- The informed consent process is conducted prior to the self-administration of this medication
- Come to the research visit with a driver
Where it is running
1 location listed across 1 US state.
- University of Wisconsin - Madison, Wisconsin, United States