WAter Preparation in Crohn's Disease's Imagery
Recruiting · NCT06690632 · Interventional (participants receive a specific treatment) · Lead sponsor: University Hospital, Toulouse
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
The goal of this clinical trial is to compare distension quality and patient experience of water and polyethylene glycol preparation as oral contrast media in Magnetic Resonance Enterography (MRE) in patients with Crohn's disease. Thus, the main question it aims to answer is: Is water sufficient to interpret MRE from patients with Crohn's disease? Researchers will compare the standard protocol (polyethylene glycol) with water as bowel distension agent to see if it is possible to obtain a satisfying global distension of small bowel. Participants will undergo the same procedures as standard care adding questionnaires and replacing water as the bowel distension agent for the MRE for patient randomized into the experimental group.
Who can take part
Inclusion criteria
- Diagnosis of Crohn's Disease,
- need for MRE (determined by patient's gastroenterologist)
Exclusion criteria
- \< 18 years old,
- inability to obtain an informed consent,
- patient under guardianship or curatorship, allergy to PEG,
- contraindication to MRE (pregnancy, pace maker, claustrophobia in particular), - contraindication to phloroglucinol administration (phenylcetonuria),
- contraindication to gadolinium administration (kidney failure with glomerular filtration rate \< 30/mL/1.73m², pregnancy, allergy).
Where it is running
1 location listed.
- CHU Toulouse - Toulouse, France