Jockey Club Precision Prevention Programme on Young Onset Diabetes

Recruiting · NCT06693934 · Interventional (participants receive a specific treatment) · Lead sponsor: Juliana CN Chan

View the official record on ClinicalTrials.gov →

Interventions studied

Continuous glucose monitoring (CGM) devices and/or weighing scaleEducation webinars, workshops and health messagesJoint Asia Diabetes Evaluation (JADE) assessmentMedicationOral glucose tolerance test (OGTT) and cardiovascular-kidney-metabolic (CKM) risk factorsRisk assessment with biogenetic and clinical test to predict diabetes riskVisit to family doctor with nurse education

What this trial is about

This is a community-based implementation program consisting of multiple components delivered by a multidisciplinary team to detect and prevent young onset diabetes with precision and value using biogenetic markers, digital tools, integrated care through public private partnership. Adults aged between 18 and 44 (inclusive) without known diabetes and with at least one risk factor for diabetes will undergo a saliva DNA and capillary blood test and complete a questionnaire. Depending on their risk levels, participants will be stratified to high risk and low risk progressors to diabetes. The high risk progressors will undergo annual oral glucose tolerance test to detect diabetes and impaired glucose tolerance (IGT). All participants will receive a personalized report indicating their genetic and modifiable risk explained by nurses or doctors. All participants will be offered regular access to webinars for education and empowerment for 2 years. The high risk group will additionally receive a 2-year risk-stratified intervention with different combinations of care interventions. These include clinical and laboratory assessment for comprehensive evaluation of cardiovascular-kidney-metabolic risks, medical and nurse consultations, empowerment by health messages, webinars, face-to-face workshops, subsidies for medications and self-monitoring tools (e.g. CGM devices, weighing scale) to motivate behavioural change. The outcomes will be analysed within the REAIM framework (reach, effectiveness, adoption, implementation and maintenance), progresssion to prediabetes or diabetes, patient reported outcomes and cost effectiveness.

Who can take part

Age range

18 Years to 44 Years

Sex

All (male and female)

Healthy volunteers

Yes - healthy volunteers may be accepted

Phase

Not applicable (e.g. observational or device study)

Study type

Interventional (participants receive a specific treatment)

Inclusion criteria

Aged between 18 and 44 years old
With at least one risk factor for diabetes

Exclusion criteria

Known history of Diabetes
With conditions considered not suitable by the project team (including illiteracy)
The risk factors for diabetes include central or general obesity, family history of diabetes, smoking history, history of hypertension/ high blood glucose level/ abnormal lipid level/ vascular disease/ fatty liver, history of gestational diabetes/ polycystic ovary syndrome/ delivery of baby≥ 4kg (for women only), and less than 150mins of physical activity every week.

Where it is running

2 locations listed.

Asia Diabetes Foundation - Hong Kong, Hong Kong
Asia Diabetes Foundation - Hong Kong, Hong Kong

Read the full protocol, contacts and eligibility on ClinicalTrials.gov →