Evaluation of IGRA, Symptoms and Chest Radiograph for Subclinical TB Detection in ESRD and KT
Recruiting · NCT06700876 · Observational (researchers observe without assigning treatment) · Lead sponsor: Mahidol University
View the official record on ClinicalTrials.gov →What this trial is about
This is an observational study among approximately 160 end-stage renal disease patients on renal replacement therapy and post-living donor or deceased donor kidney transplant recipients. Investigators aim to assess the proportion of positive IGRA associated with symptom development, sputum Xpert MTB/RIF assay, and chest radiograph to define latent TB infection and subclinical TB among ESKD and renal transplant patients.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- End-stage renal disease on renal replacement therapy (hemodialysis or peritoneal dialysis) or status-post-living donor or deceased donor kidney transplantation
- Aged more than or equal 18 years
Exclusion criteria
- Positive PPD test or a previously documented positive PPD
- Active pulmonary or extrapulmonary tuberculosis
Where it is running
1 location listed.
- Vaccine Trial Centre, Faculty of Tropical Medicine, Mahidol University - Bangkok, Thailand