Evaluation of Long-Acting Injectable (LAI) and Teen Clubs in Adolescents (ATTUNE).
Recruiting · NCT06721078 · Interventional (participants receive a specific treatment) · Lead sponsor: Africa Health Research Institute
View the official record on ClinicalTrials.gov →Interventions studied
Peer navigation effectiveness
What this trial is about
This is a 2-stage study assessing the effect of peer navigation (support from peers) and long-acting injectable antiretroviral therapy (ART) on viral suppression and retention in care among adolescents living with HIV and receiving care in South Africa.
Who can take part
Age range
12 Years to 19 Years
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Aged between 12 - \<19, at enrolment
- Living with HIV
- Aware of their HIV status
- Receiving ART for at least six months
- Able to read and/or speak English, isiZulu, Sepedi, Afrikaans, Xhosa, or Sesotho
- Willing and able to consent to study activities
- Willing and able to get parental consent for study activities
- (Stage 1, objective 2 only) Age ≥ 18 years and Caregiver of an adolescent with HIV
- (Stage 1, objective 2 only) Age ≥ 18 years and provides clinical services or is a policy maker involved in adolescents with HIV
Exclusion criteria
- Inability to read and/or speak English, isiZulu, Sepedi, Afrikaans, Xhosa, or Sesotho
- Severe mental or physical illness preventing participation in informed consent activities.
Where it is running
12 locations listed.
- Charlotte Maxeke Hospital - Johannesburg, Gauteng, South Africa
- Rahima Moosa Mother and Child Hospital - Johannesburg, Gauteng, South Africa
- Kgabo CHC - Pretoria, Gauteng, South Africa
- KT Motubatse CHC - Pretoria, Gauteng, South Africa
- Soshanguve Block JJ - Pretoria, Gauteng, South Africa
- Soshanguve Block TT - Pretoria, Gauteng, South Africa
- Cato Manor CHC - Durban, KwaZulu-Natal, South Africa
- KwaMashu CHC - Durban, KwaZulu-Natal, South Africa
- Mtubatuba CHC - Mtubatuba, KwaZulu-Natal, South Africa
- Somkhele CHC - Mtubatuba, KwaZulu-Natal, South Africa
- Eerste River Hospital - Cape Town, Western Cape, South Africa
- Michael Mapongwana CHC - Cape Town, Western Cape, South Africa