DAANCE FOR CHEMOTHERAPY-INDUCED NEUROPATHY
Recruiting · NCT06749210 · Interventional (participants receive a specific treatment) · Lead sponsor: Ohio State University Comprehensive Cancer Center
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
Up to 80% of breast cancer survivors experience chemotherapy-induced neuropathy that impairs quality of life and increases fall risk long into survivorship, yet treatment options for neuropathy remain limited. The successful treatment will target neurophysiologic mechanisms for restoring function while addressing patient-reported symptoms and participation in treatment. Toward this end, the investigators propose to study a noninvasive, social sensorimotor intervention - Adapted Argentine Tango - which targets motor control restoration, symptom alleviation, and treatment participation in concert.
Who can take part
Inclusion criteria
- Breast Cancer (BC) diagnosis of Stage I-IV including metastatic disease
- completed taxane-based chemotherapy for BC at least 3 months ago (no limit on how long ago)
- symptomatic for chemotherapy-induced neuropathy (self-report)
- postural control score that indicates potential fall-risk
- able to understand and comply with directions associated with testing and study treatments
Exclusion criteria
- pre-existing vestibular dysfunction
- poorly controlled diabetes (hgA1C\>=8)
- non-ambulatory (assistive and prosthetic devices allowed)
- hearing impairment resulting in less than 10% hearing bilaterally
- contraindication to participate in the experimental physical activity per the treating oncologist due to additional condition (e.g., herniated disc, unstable bone metastases)
- currently in activity-based therapy (e.g., physical therapy, occupational therapy). May enroll if still meet eligibility criteria once activity-based therapy is complete.
Where it is running
2 locations listed across 2 US states.
- Yale University - New Haven, Connecticut, United States
- The Ohio State University - Columbus, Ohio, United States