Phenotype-Tailored Lifestyle Intervention for Obesity: A Randomized Trial
Recruiting · NCT06770049 · Interventional (participants receive a specific treatment) · Lead sponsor: Mayo Clinic
View the official record on ClinicalTrials.gov →Interventions studied
Phenotype-tailored Lifestyle Intervention (PLI) programStandard Lifestyle Intervention (SLI) program
What this trial is about
The purpose of this study is to develop an evidence-based precision medicine approach for obesity that enhances weight loss and promotes weight loss maintenance.
Who can take part
Age range
18 Years to 65 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Eligibility criteria (as published)
Inclusion:
• men or women between 18 to 65 years with obesity (BMI\>30kg/m2).
Exclusion:
* weight change greater than 3% in the previous 3 months
* history of bariatric surgery and bariatric endoscopy
* untreated psychiatric disorders including binge eating disorders and bulimia
* current use of AOMs
* history of use of medications affecting weight or energy intake or energy expenditure in the last 6 months
* history of type 1 diabetes mellitus or uncontrolled medical conditions (e.g., uncontrolled hypertension)
* women who are pregnant or plan to become pregnant,
* any condition that limits their participation in the study
* Principal Investigator discretion
Where it is running
1 location listed across 1 US state.
- Mayo Clinic - Rochester, Minnesota, United States