MR Elastography for Assessing Liver Fibrosis in Chronic Hepatitis B
Recruiting · NCT06779058 · Observational (researchers observe without assigning treatment) · Lead sponsor: Shengjing Hospital
View the official record on ClinicalTrials.gov →Interventions studied
Liver biopsyMRE
What this trial is about
How to construct a non-invasive, accurate, and convenient method to evaluate the severity of liver fibrosis (LF) is an important general problem in the management of patients with chronic hepatitis B (CHB). We plan to investigate the ability of magnetic resonance elastography (MRE) to grade fibrosis in chronic hepatitis B and apply to clinical longitudinal follow-up.
Who can take part
Age range
18 Years to 80 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Age ≥ 18 years old
- Confirmed CHB (laboratory, imaging and clinical tests)
- MRE within 6 months before and after liver biopsy
- Treatment-naïve
- Child-Pugh Grade A (\<7 points)
- Written informed consent in prospective follow-up cohort
Exclusion criteria
- Patients with liver malignant tumor
- Chronic hepatitis due to other causes (such as alcoholic hepatitis)
- CHB combined with hepatitis C, hepatitis D, or HIV
- Patients with biliary tract diseases
- Contraindications of MRE examination, MRE failure
- Poor pathological effect
Where it is running
1 location listed.
- Shengjing Hospital - Shenyang, Liaoning, China