A Study to Investigate Effects of Ocrelizumab Treatment on Neurofilament Light Chain (NfL) Levels and Participant Satisfaction in Participants With Multiple Sclerosis (MS)
Recruiting · NCT06780150 · Observational (researchers observe without assigning treatment) · Lead sponsor: Hoffmann-La Roche
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
The main purpose of the study is to evaluate participant satisfaction after administration of ocrelizumab subcutaneously (SC) after 12 months using the therapy administration satisfaction questionnaire subcutaneous (TASQ-SC).
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Diagnosis of MS
- RMS and PPMS participants diagnosed according to the McDonald criteria of 2017 or revised McDonald criteria 2024
- First treatment during the course of MS therapy with ocrelizumab SC according to the local prescribing information, regardless of the reason for starting treatment with ocrelizumab
Exclusion criteria
- Participation in interventional studies investigating DMTs for MS
- Prior or simultaneous participation in CONFIDENCE or MoOzaRt (ISRCTN55332718) non interventional study (NIS) at the same study site
- Prior treatment with rituximab (MabThera®) or ublituximab (Briumvi®)
- Severe psychiatric disability
- Pregnant women
Where it is running
60 locations listed.
- Uniklinik RWTH Aachen - Aachen, Germany
- Gesundheitszentrum St. Marien GmbH - Amberg, Germany
- Sächsisches Krankenhaus Arnsdorf - Arnsdorf, Germany
- Neuropraxis im Stadtpalais Dres. Ulzheimer/Herröder/Wessig GbR - Aschaffenburg, Germany
- Neurologie Bad Soden - Bad Soden, Germany
- Neurologische Praxis - Kallmann Neurologie - mszb - Bamberg, Germany
- Marianne-Strauß-klinik - Berg, Germany
- Neurologisches Facharztzentrum Berlin am Sankt Gertrauden-Krankenhaus - Berlin, Germany
- NEUROZENTRUM tempelhof.berlin - Berlin, Germany
- Praxis Dr. Said Masri - Berlin, Germany
- Jüdisches Krankenhaus Berlin - Berlin, Germany
- NeuroZentrum Zehlendorf Dr. Ringel und Dr. Scherer - Berlin, Germany
- Neurologisches Zentrum für Bewegungsstörungen und Diagnostik - Berlin, Germany
- Inselspital-Universitaetsspital Bern - Bern, Switzerland
- St. Josef-Hospital - Bochum, Germany
- Dres. Lippert/Kausch - Bogen, Germany
- Krankenhaus Buchholz Abt. Neurologie - Buchholz, Germany
- Allgemeines Krankenhaus Celle / Klinik für Neurologie - Celle, Germany
- Neuropraxis Celle: Praxis für Neurologie & Psychatrie - Celle, Germany
- Praxisgemeinschaft Dres. Sylke Domke und Vasil Gjaurov - Chemnitz, Germany
- NeuroMed Campus Neurologische Gemeinschaftspraxis am St. Elisabeth Krankenhaus - Cologne, Germany
- Gemeinschaftspraxis Dr. med. Josef Leclaire und Dr. med. Thomas Rotermund - Dortmund, Germany
- Gemeinschaftspraxis für Neurologie - Düsseldorf, Germany
- Universitätsklinikum Düsseldorf - Düsseldorf, Germany
- Nervenarztpraxis Gerresheim - Düsseldorf, Germany
- Gemeinschaftspraxis für Neurologie und Psychiatrie, Psychotherapie - Eltville, Germany
- NeuroCentrum Odenwald - Erbach/Odenwald, Germany
- Universitätsklinikum Erlangen, Neurologische Klinik - Erlangen, Germany
- Zentrum für ambulante Neurologie / Praxis Knorn Landefeld Friedrich - Essen, Germany
- Praxis Nervenstark - Essen, Germany
- Praxis für Neurologie, Nervenheilkunde & Neurochirurgie - Forchheim, Germany
- Klinikum Joh.Wolfg.Goethe-UNI Senckenbergisches Institut für Neuroonkologie - Frankfurt, Germany
- Varisano Klinikum Frankfurt Höchst GmbH - Frankfurt, Germany
- Universitätsklinikum Freiburg, Klinik für Neurologie und Neurophysiologie - Freiburg im Breisgau, Germany
- Praxis im Bahnhof - Füssen, Germany
- Universitätsklinikum Gießen und Marburg GmbH - Giessen, Germany
- Neurologie & Psychiatrie Gladenbach - MS-Zentrum - Gladenbach, Germany
- MVZ Bezirkskliniken Schwaben, Standort Günzburg - Günzburg, Germany
- Krankenhaus Martha-Maria Halle-Doelau - Halle, Germany
- Universiätsklinikum Hamburg-Eppendorf - Hamburg, Germany
- Neurologische Praxis Eppendorf - Hamburg, Germany
- Neurologische Praxis - Hanover, Germany
- Oberhavel Kliniken GmbH, Klinik Hennigsdorf, Neurologie - Hennigsdorf, Germany
- Praxis Dr. Hospely - Herford, Germany
- Haus- und Facharztzentrum Laucherttal / Alb - Hettingen, Germany
- Klinikum Ibbenbüren gmbH - Ibbenbueren, Germany
- Augustahospital Anholt;Neurologie - Isselburg, Germany
- Universitätsklinikum Jena, Klinik für Neurologie - Jena, Germany
- Uniklinik Schleswig-Holstein - Kiel, Germany
- Arztpraxis Dr. med. Torsten Sühnel - Leipzig, Germany
- Neurologische Praxis Dr. Ehrlich - Leipzig, Germany
- Universitätsklinik Schleswig Holstein, Campus Lübeck - Lübeck, Germany
- Neurologie im Ulrichshaus Magdeburg - Magdeburg, Germany
- Universitätsklinikum Magdeburg - Magdeburg, Germany
- Neuroplus Dres. Lennart Thilmann/ Patrick Thilmann - Mannheim, Germany
- Universitätsklinikum Mannheim - Mannheim, Germany
- Universitätsklinikum Giessen und Marburg - Marburg, Germany
- Praxis Dr. Leussink - Meerbusch, Germany
- Neurologie am Preußenmuseum - Minden, Germany
- Neurologie München Nord - München, Germany
Showing 60 of 92 listed sites. See the official record for the complete list.
Read the full protocol, contacts and eligibility on ClinicalTrials.gov →