Supplemental High Flow Oxygen to Reduce Infections in Obese Gynecological Cancer Patients
Recruiting · NCT06780813 · Interventional (participants receive a specific treatment) · Lead sponsor: National and Kapodistrian University of Athens
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
The incidence of surgical-site infection (SSI) and complications related to wound healing reaches 10-20% of gynecological cancer patients. Each complication may dramatically prolong the hospitalization period and increase the economic burden of hospital care. Appropriate wound care and tissue oxygenation are of special importance for wound healing. Assuming adequate perfusion, the easiest, safest, and most effective way to improve tissue oxygenation is to increase the fraction of inspired oxygen. However, there is considerable controversy as to whether supplemental oxygen actually reduces SSI and healing-related complications as to date, there is absence of relevant data.
Who can take part
Inclusion criteria
- Obese (BMI\>30kg/m2) gynecological cancer patients
- Optimized preoperative CBC values (hemoglobin \>11g/dl, WBC 4.000-11.000 X 109/L, platelets 150,000 to 400,000 X 109/L)
- In the case of neoadjuvant therapy an interval longer than three weeks between the last cycle and the operation
Exclusion criteria
- Active immunosuppresion
- Preexisting infection of the abdominal wall
- Preexisting sepsis
Where it is running
1 location listed.
- First department of Obstetrics and Gynecology - Athens, Greece