Periodontal Microbiota of Patients Candidates for Bariatric Surgery With Body Mass Index Greater Than 30
Recruiting · NCT06781229 · Observational (researchers observe without assigning treatment) · Lead sponsor: University Hospital, Toulouse
View the official record on ClinicalTrials.gov →What this trial is about
The goal of this observational study is to compare the microbiological composition of the periodontal plaque of obese people undergoing bariatric surgery according to their Body Mass Index. The main question it aims to answer is: Does obese patients have different microbiote according to their obesity? Obesity being classified in two groups : * group "obesity" for a BMI between 30 and 35 * versus "morbid obesity" group with a BMIabove 35. Participants who are scheduled to undergo bariatric surgery as part of their regular medical care will answer questions about their quality of life, hygiene habits, and saliva and periodontal samples will be taken.
Who can take part
Inclusion criteria
- BMI greater than or equal to 30
- Be on the list of patients scheduled for bariatric surgery,
- Be able to receive information about the study and understand the information form in order to take part in the study. This implies mastering the French language,
Exclusion criteria
- Alcohol consumption \>30g/d (men) or 20g/d (women),
- Having taken antibiotics, prebiotics or probiotics in the month prior to inclusion (this has an influence on the composition of the patient's microbiota),
- During pregnancy or breastfeeding,
- For whom oral surgery is planned (surgery for benign or malignant tumours of the maxillary and mandibular bone bases), or with a history of oral surgery in the month prior to inclusion,
- At risk of infection (existence of one or more of the following known chronic infectious diseases: HIV, HBV, HCV and mononucleosis) and/or chronic renal insufficiency (creatinine clearance \< 60ml/min),
- Patients with a general pathology that contraindicates the performance of diagnostic procedures such as periodontal probing (patients at high risk of infective endocarditis according to the ANSM).
- Totally edentulous patients
Where it is running
1 location listed.
- University Hospital of Toulouse - Toulouse, France