Copeptin and Thirst: Possible Predictive Markers of Effectiveness of Bariatric Surgery?

Recruiting · NCT06806787 · Observational (researchers observe without assigning treatment)

What this trial is about

Prospective, non-pharmacological, spontaneous, single-center, interventional study.

Age range

18 Years to 65 Years

Sex

All (male and female)

Healthy volunteers

No - a diagnosis or condition is required

Phase

Not specified

Study type

Observational (researchers observe without assigning treatment)

BMI ≥ 40 in the absence of comorbidities; BMI ≥ 35 associated with at least one comorbidity
Age ≥ 18 and less than or equal to 65 years
Written informed consent obtained

Contraindications to bariatric surgery:
severe psychiatric illness in the decompensation phase;
drug or alcohol abuse;
patient unwilling to follow periodic checkups and a dietary regimen pregnancy or lactation.
Factors that could alter ADH/copeptin:
Obesity induced by other endocrinopathies or medications;
Diabetes mellitus of any type;
Malignant neoplasms or ongoing acute disease;
Organ failure or chronic CNS and kidney disease;
Hydro-electrolyte alterations;
use of drugs that interfere with pituitary-adrenal axis, diuretics, anti-psychotics and psychopharmacological therapies, GLP1 receptor agonists, estro-progestin therapy.

1 location listed.