Anti-hypertensive Therapy and Exercise Treatment to Improve Vascular Health in Patients With Hypertension.
Recruiting · NCT06823570 · Interventional (participants receive a specific treatment) · Lead sponsor: Heinrich-Heine University, Duesseldorf
View the official record on ClinicalTrials.gov →Interventions studied
Individualized exercise therapyLifestyle recommendations
What this trial is about
This is a prospective, monocentric, randomized controlled trial to investigate the effect of anti-hypertensive treatment and/or individualized exercise training intervention on blood pressure and vascular health. Furthermore the investigators want to decipher mechanisms, which contribute to vascular health by analyzing changes in metabolism and cell function in relation to vascular reaction.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- \- systolic hypertension grade I-II (BP values \>140 mmHg to \<180 mmHg) without anti-hypertensive medication treatment
Exclusion criteria
- no written informed consent
- age \<18 years
- isolated diastolic hypertension
- medical contraindications for the exercise treatment (for example orthopedic problems or an abnormal ECG during the cardio respiratory exercise test)
- chronic eye diseases on both eyes (for example macular degeneration or glaucoma) or high intraocular pressure (\>20 mmHg)
Where it is running
1 location listed.
- Universitätsklinik Düsseldorf - Düsseldorf, Düsseldorf, Germany