Association Between Genetic Polymorphisms and Type 2 Asthma in Children
Recruiting · NCT06840717 · Observational (researchers observe without assigning treatment) · Lead sponsor: Guangzhou Institute of Respiratory Disease
View the official record on ClinicalTrials.gov →What this trial is about
To further understand the role of gene single nucleotide polymorphism (SNP) in the occurrence of type 2 inflammation-related asthma in children by analyzing the gene single nucleotide polymorphism (SNP), lung function and type 2 inflammation indicators of children diagnosed with asthma in outpatient and inpatient. To provide a theoretical basis for the study of personalized treatment and prevention strategies for asthma.
Who can take part
Age range
3 Years to 14 Years
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- All children with asthma diagnosis accord with the GINA in 2023 edition;
- Other diseases that could cause wheezing and cough were excluded, such as acute laryngitis, diphtheria, congenital airway abnormalities, and tracheal foreign bodies;
- In front of the hospital 2 weeks without antibiotics, systemic hormone medication history;
- There were no other complications, such as congenital heart disease, pneumonia, gastroesophageal reflux disease, muscle dysplasia, etc.
Exclusion criteria
- Children who had taken immunosuppressants, antibiotics and other drugs for a long time before admission;
- Children with primary immunodeficiency disease;
- The children and their families failed to cooperate or refused the experimental observation.
Where it is running
1 location listed.
- Guangzhou institute of respiratory disease - Guangzhou, Guangdong, China