Prediction of Blood Pressure Outcomes Following Renal Denervation (PREDICT-RDN)
Recruiting · NCT06845579 · Interventional (participants receive a specific treatment) · Lead sponsor: Heart Center Leipzig - University Hospital
View the official record on ClinicalTrials.gov →Interventions studied
Renal sympathetic denervation
What this trial is about
Prospective, single arm trial to assess the effects of renal denervation on day-by-day blood pressure measurements and time in blood pressure target range, as well as establish a multivariate prediction model for blood pressure reduction after renal denervation.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Confirmed arterial hypertension with systolic or diastolic blood pressure \>140/90 mmHg in standardized office blood pressure measurement
- Treatment with 3 to ≤5 antihypertensive drug classes
- Age \>18 years
- Written informed consent
Exclusion criteria
- Age ≤ 18 years
- anatomy unsuitable for renal denervation (i.e. renal artery stenosis, single functioning kidney)
- pregnancy
- patients under legal supervision or guardianship
- participation in other trials that might interfere with the study outcome according to the opinion of one of the investigators.
Where it is running
2 locations listed.
- Universitätsmedizin Mainz Kardiologie I - Mainz, Rheinland Pflanz, Germany
- Heart Center Leipzig - Leipzig, Saxony, Germany