Real World Clinical Outcomes of Resected ALK-Positive Early Stage NSCLC Patients Treated With Alectinib as Adjuvant Therapy
Recruiting · NCT06862869 · Observational (researchers observe without assigning treatment) · Lead sponsor: Hoffmann-La Roche
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
This study is a multicenter, prospective, cohort study designed to evaluate the clinical outcomes and characteristics of resected stage II-IIIB anaplastic lymphoma kinase (ALK)-positive non-small-cell lung cancer (NSCLC) adult patients treated with Alectinib as adjuvant therapy in China.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Histologically-confirmed stage II-IIIA or selected IIIB (T3N2) NSCLC as per the American Joint Committee on Cancer and International Union Against Cancer (UICC/AJCC), 8th edition
- ALK positive
- Postoperative NSCLC patients who have undergone complete resection
- Had taken Alectinib monotherapy without prior systemic therapy (including other ALK-TKIs or chemotherapy) as adjuvant† therapy for resected stage II-IIIB ALKpositive NSCLC and the time from the first dose to enrollment was no more than 28 days
Exclusion criteria
- Patients participating in interventional study of adjuvant treatment
- Pregnant, lactating, or breastfeeding women
Where it is running
44 locations listed.
- Peking University First Hospital - Beijing, China
- Xuanwu Hospital, Capital Medical University - Beijing, China
- Hunan Cancer Hospital - Changsha, China
- Changzhou First People's Hospital - Changzhou, China
- Sichuan Academy of Medical Sciences and Sichuan Provincial Peoples Hospital - Chengdu, China
- The First Affiliated Hospital, Chongqing Medical University - Chongqing, China
- The Second Affiliated Hospital of Dalian Medical University - Dalian, China
- Fujian Cancer Hospital - Fuzhou, China
- The Third Affiliated Hospital of Sun Yat-Sen University - Guangzhou, China
- The Second Affiliated Hospital, Zhejiang University - Hangzhou, China
- Zhejiang Cancer Hospital - Hangzhou, China
- Harbin Medical University Cancer Hospital - Harbin, China
- Anhui Provincial Hospital - Hefei, China
- Huzhou Central Hospital - Huzhou, China
- Jiangmen Central Hospital - Jiangmen, China
- Shandong Provincial Hospital - Jinan, China
- Lanzhou University Second Hospital - Lanzhou, China
- The First Affiliated Hospital of Nanchang University - Nanchang, China
- Jiangsu Cancer Hospital - Nanjing, China
- Jiangsu Province Hospital - Nanjing, China
- Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School - Nanjing, China
- Affiliated Hospital of Nantong University - Nantong, China
- Ningbo No.2 Hospital - Ningbo, China
- Shanghai Chest Hospital - Shanghai, China
- Zhongshan Hospital Fudan University - Shanghai, China
- Shanghai Pulmonary Hospital - Shanghai, China
- Liaoning Provincial Cancer Hospital - Shengyang, China
- Cancer Hospital Chinese Academy of Medical Sciences Shenzhen Center - Shenzhen, China
- Hebei Medical University Fourth Hospital - Shijiazhuang, China
- Shanxi Provincial Cancer Hospital - Taiyuan, China
- Taizhou Hospital of Zhejiang Province - Taizhou, China
- Chest disease hospital of Tianjin City - Tianjin, China
- Wuhan Union Hospital Tongji Medical College, Huazhong University of Science and Technology - Wuhan, China
- Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science & Technology - Wuhan, China
- Wuxi People's Hospital - Wuxi, China
- The Second Affiliated Hospital of Xi'an Jiao Tong University - Xi'an, China
- Xi'an International Medical Center Hospital - Xi'an, China
- General Hospital of Ningxia Medical University - Yinchuan, China
- Affiliated Hospital of Zunyi Medical University - Zunyi, China
- Affiliated Hospital of Guangdong Medical University - Zhanjiang, Guangdong, China
- Affiliated Cancer Hospital and Institute of Guangzhou Medical University - Guangzhou, Guangzhou, China
- Huai He Hospital of Henan University - Kaifeng, Henan, China
- Henan Provincial Chest Hospital - Zhengzhou, Henan, China
- The First Affiliated Hospital of Xinjiang Medical University - Ürümqi, Xinjiang, China