Duloxetine Metabolism and Fibromyalgia
Recruiting · NCT06866444 · Observational (researchers observe without assigning treatment) · Lead sponsor: University of Utah
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
People with fibromyalgia report generalized body pain ("pain all over"), increased sensitivity to painful stimulation, chronic tiredness or low energy, sleep problems, and other physical and functional problems. The exact cause of the disorder is poorly understood, and treatment can be difficult. The degree to which duloxetine is helpful for people with fibromyalgia varies greatly. For some people, it is very helpful for managing fibromyalgia symptoms. For others, people may not notice any benefit. Yet for some, it is a little helpful and the effect is noticeable only when people forget to take the medicine. The purpose of this study is to collect data to better understand the relationship among gene types that control those enzymes, blood concentrations of duloxetine, and how it helps the symptoms.
Who can take part
Inclusion criteria
- Adults 18+
- Meeting diagnostic criteria for Fibromyalgia
- Patients taking Duloxetine 60 mg/day for at least 8 weeks
Exclusion criteria
- Pregnant patients per verbal confirmation
- Patients that have a history of physician diagnosed kidney or liver disfunction or history of renal dialysis.
- Patients requiring an interpreter to communicate
- Patient's with progressive illnesses other than fibromyalgia that have a chronic pain and fatigue component (e.g., cancer patients receiving antineoplastic treatment, Parkinson's disease, Multiple Sclerosis).
Where it is running
1 location listed across 1 US state.
- Pain Management Center and Pain Research Center at the University of Utah - Salt Lake City, Utah, United States